Photonic crystal microring resonator for label-free biosensing.

نویسندگان

  • Stanley M Lo
  • Shuren Hu
  • Girija Gaur
  • Yiorgos Kostoulas
  • Sharon M Weiss
  • Philippe M Fauchet
چکیده

A label-free optical biosensor based on a one-dimensional photonic crystal microring resonator with enhanced light-matter interaction is demonstrated. More than a 2-fold improvement in volumetric and surface sensing sensitivity is achieved compared to conventional microring sensors. The experimental bulk detection sensitivity is ~248nm/RIU and label-free detection of DNA and proteins is reported at the nanomolar scale. With a minimum feature size greater than 100nm, the photonic crystal microring resonator biosensor can be fabricated with the same standard lithographic techniques used to mass fabricate conventional microring resonators.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Silicon photonic sensors incorporated in a digital microfluidic system.

Label-free biosensing with silicon nanophotonic microring resonator sensors has proven to be an excellent sensing technique for achieving high-throughput and high sensitivity, comparing favorably with other labeled and label-free sensing techniques. However, as in any biosensing platform, silicon nanophotonic microring resonator sensors require a fluidic component which allows the continuous de...

متن کامل

Label-free biosensing using a photonic crystal structure in a total-internal-reflection geometry.

A novel optical biosensor using a one-dimensional photonic crystal structure in a total-internal-reflection geometry (PC-TIR) is presented and investigated for label-free biosensing applications. This simple configuration forms a micro Fabry-Perot resonator in the top layer which provides a narrow optical resonance to enable label-free, highly sensitive measurements for the presence of analytes...

متن کامل

Label-Free Optical Detection of Fibrinogen in Visible Region Using Nanoimprint Lithography-Based Two-Dimensional Photonic Crystal

For the future medical diagnostics, high-sensitive, rapid, and cost effective biosensors to detect the biomarkers have been desired. In this study, the polymer-based two-dimensional photonic crystal (2DPC) was fabricated using nanoimprint lithography (NIL) for biosensing application. In addition, for biosensing application, label-free detection of fibrinogen which is a biomarker to diagnose the...

متن کامل

Dextran Modified Silicon Photonic Microring Resonator Sensors

We present a dextran modified silicon microring resonator sensor for high density antibody immobilization. An array of sensors consisting of three sensor rings and a reference ring was fabricated and its surface sensitivity and the limit of detection were obtained using polyelectrolyte multilayers. The mass sensitivity and the limit of detection of the fabricated sensor ring are 0.35 nm/ng mm a...

متن کامل

The New Design and Simulation of an Optical Add Drop Filter Based On Hexagonal Photonic Crystal Single Ring Race Track Resonator

In this paper, using annular resonator we have designed an adding and dropping filter light based ontwo-dimensional photonic crystals. The shape of ring resonator filter adding and dropping that wehave proposed is Race Track. This filter has a hexagonal lattice structure of silicon bars withrefractive index 3/46 that is located in the context of air with refractive index 1. Transmissionefficien...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Optics express

دوره 25 6  شماره 

صفحات  -

تاریخ انتشار 2017